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KMID : 1098420150230050363
Korean Journal of Medicinal Crop Science
2015 Volume.23 No. 5 p.363 ~ p.369
Effect of Saponin Content and Antioxidant Activities of Platycodon grandiflorum Radix by Cutting Length
Lee Byung-Jin

Jeon Seung-Ho
No Il-Rae
Kim Young-Guk
Cho Young-Son
Abstract
Background : Platycodon grandiflorum radix used as a therapeutic agent for lung and respiratory diseases in traditional Korean medicine. The saponin and sugar content in P. grandiflorum root is dependent on the drying temperature and method. In this study, we investigated saponins and antioxidant contents in dried P. grandiflorum roots either not cut or cut to different lengths.

Methods and Results : P. grandiflorum roots were either cut to 0.5, 1.0 or 2.0 §¯ in length or left uncut. They were dried at 45¡É and the effect of antioxidant substances, antioxidant ability, and saponin content were investigated. P. grandiflorum roots rapidly dried out when cut to short lengths. The saponin contents (platycodin D, polygalacin D, and deapioplatycodin D) was highest in the uncut P. grandiflorum roots. When the cut lengths were long, the levels of polyphenolic compound increased. However, 2,2'-azinobis-3-ethylbenzo-thiazoline-6-sulfonic acid (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities were higher in the samples cut to shorter lengths.

Conclusions : These results suggested that the saponin and antioxidant content of P. grandiflorum roots could be maximized by controlling the drying rate of the roots via adjustments to the root cutting length.
KEYWORD
Platycodon grandiflorum, Antioxidant, ABTS Radical, DPPH Radical, Saponin
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